Rectal suppositories seemed promising for at least two reasons. First, they go to work quickly. Suppositories exert systemic effects when they enter the rectal mucosa, spreading healing compounds quickly through nearby organs and into the bloodstream. Second, it’s an effective way of diminishing the “head-high” psychoactive effects of THC.
The benefits of suppositories—combined with how easy it is to make them at home—has made them quite popular, especially in Central Europe.